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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RPS6KA4
All Species:
31.52
Human Site:
S402
Identified Species:
46.22
UniProt:
O75676
Number Species:
15
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75676
NP_001006945.1
772
85606
S402
R
S
A
M
M
Q
D
S
P
F
F
Q
Q
Y
E
Chimpanzee
Pan troglodytes
XP_508900
901
98668
S531
R
S
A
M
M
Q
D
S
P
F
F
Q
Q
Y
E
Rhesus Macaque
Macaca mulatta
XP_001114877
772
85557
S402
R
S
A
M
M
Q
D
S
P
F
F
Q
Q
Y
E
Dog
Lupus familis
XP_854926
772
85603
S403
R
S
A
M
M
Q
D
S
P
F
F
Q
Q
Y
E
Cat
Felis silvestris
Mouse
Mus musculus
Q9Z2B9
773
85721
S402
R
S
A
M
M
Q
D
S
P
F
F
Q
Q
Y
E
Rat
Rattus norvegicus
Q63531
735
82865
R377
A
G
A
H
Q
L
F
R
G
F
S
F
V
A
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506738
716
80894
H339
K
D
S
P
F
Y
Q
H
Y
D
L
D
L
K
D
Chicken
Gallus gallus
Q5F3L1
789
89022
S407
R
S
A
M
M
K
D
S
P
F
F
Q
H
Y
E
Frog
Xenopus laevis
P10665
733
82620
S380
H
Q
L
F
R
G
F
S
F
V
A
P
A
L
V
Zebra Danio
Brachydanio rerio
Q6PFQ0
740
83378
F384
A
H
Q
L
F
K
G
F
S
F
V
A
P
V
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V3I5
1207
137026
I616
F
N
T
G
L
Q
N
I
P
C
R
P
D
D
L
Honey Bee
Apis mellifera
XP_395099
910
102507
S442
L
A
A
R
F
E
E
S
T
F
F
Q
S
Y
E
Nematode Worm
Caenorhab. elegans
Q18846
772
87050
S373
N
A
L
L
A
S
S
S
F
F
A
K
Y
K
L
Sea Urchin
Strong. purpuratus
XP_786494
918
102561
S376
S
I
H
E
L
K
D
S
P
F
N
K
Y
Y
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q39030
471
53019
D120
N
D
E
F
S
G
N
D
D
T
D
S
E
K
S
Baker's Yeast
Sacchar. cerevisiae
P18961
677
76646
T328
G
Y
G
K
L
N
I
T
V
D
Y
K
P
S
K
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
85.4
98.6
96.7
N.A.
95.8
41.3
N.A.
56
64
41
41.9
N.A.
27
45.1
48.1
48.2
Protein Similarity:
100
85.6
98.9
98
N.A.
96.7
60.6
N.A.
71.6
78.4
59
60.3
N.A.
38.9
60.1
64.3
61.8
P-Site Identity:
100
100
100
100
N.A.
100
13.3
N.A.
0
86.6
6.6
6.6
N.A.
13.3
46.6
13.3
40
P-Site Similarity:
100
100
100
100
N.A.
100
13.3
N.A.
20
93.3
6.6
20
N.A.
33.3
66.6
33.3
60
Percent
Protein Identity:
N.A.
N.A.
N.A.
20.4
21.2
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
35.6
37.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
13
13
50
0
7
0
0
0
0
0
13
7
7
7
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
7
0
0
0
0
0
% C
% Asp:
0
13
0
0
0
0
44
7
7
13
7
7
7
7
7
% D
% Glu:
0
0
7
7
0
7
7
0
0
0
0
0
7
0
50
% E
% Phe:
7
0
0
13
19
0
13
7
13
69
44
7
0
0
0
% F
% Gly:
7
7
7
7
0
13
7
0
7
0
0
0
0
0
0
% G
% His:
7
7
7
7
0
0
0
7
0
0
0
0
7
0
0
% H
% Ile:
0
7
0
0
0
0
7
7
0
0
0
0
0
0
0
% I
% Lys:
7
0
0
7
0
19
0
0
0
0
0
19
0
19
7
% K
% Leu:
7
0
13
13
19
7
0
0
0
0
7
0
7
7
13
% L
% Met:
0
0
0
38
38
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
13
7
0
0
0
7
13
0
0
0
7
0
0
0
0
% N
% Pro:
0
0
0
7
0
0
0
0
50
0
0
13
13
0
0
% P
% Gln:
0
7
7
0
7
38
7
0
0
0
0
44
32
0
0
% Q
% Arg:
38
0
0
7
7
0
0
7
0
0
7
0
0
0
0
% R
% Ser:
7
38
7
0
7
7
7
63
7
0
7
7
7
7
13
% S
% Thr:
0
0
7
0
0
0
0
7
7
7
0
0
0
0
7
% T
% Val:
0
0
0
0
0
0
0
0
7
7
7
0
7
7
7
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
7
0
0
0
7
0
0
7
0
7
0
13
50
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _